Publikationen von Didier Y. R. Stainier

Falcucci, L.; Dooley, C. M.; Adamoski, D.; Juan, T.; Martinez, J.; Georgieva, A. M.; Mamchaoui, K.; Cirzi, C.; Stainier, D. Y. R.: Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy. NATURE (639(8054)), S. 493 - 502 (2025)

Gupta, S.; Bajwa, G. K.; El-Sammak, H.; Mattonet, K.; Guenther, S.; Looso, M.; Stainier, D. Y. R.; Marin-Juez, R.: The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration. DEVELOPMENTAL BIOLOGY 521, S. 153 - 162 (2025)

Juan, T.; Molina, T.; Xie, L.; Papadopoulou, S.; Cardoso, B.; Jha, S. G.; Stainier, D. Y. R.: A recombinase-activated ribozyme to knock down endogenous gene expression in zebrafish. PLOS GENETICS 21 (2), e1011594 (2025)

Juvik, B.; Falcucci, L.; Lundegaard, P. R.; Stainier, D. Y. R.: A new hypothesis to explain disease dominance. TRENDS IN GENETICS 41 (3), S. 187 - 193 (2025)

Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, P. M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)

Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)

Wang, Z.-Y.; Mehra, A.; Wang, Q.-C.; Gupta, S.; da Silva, A. R.; Juan, T.; Guenther, S.; Looso, M.; Detleffsen, J.; Stainier, D. Y. R. et al.; Marin-Juez, R.: flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response. DEVELOPMENT 151 (23), dev203028 (2024)

Prieto-Garcia, C.; Matkovic, V.; Mosler, T.; Li, C.; Liang, J.; Oo, J. A.; Haidle, F.; Macinkovic, I.; Cabrera-Orefice, A.; Berkane, R. et al.; Giuliani, G.; Xu, F.; Jacomin, A.-C.; Tomaskovic, I.; Basoglu, M.; Hoffmann, M. E.; Rathore, R.; Cetin, R.; Boutguetait, D.; Bozkurt, S.; Canas, M. C. H.; Keller, M.; Busam, J.; Shah, V. J.; Wittig, I.; Kaulich, M.; Beli, P.; Galej, W. P.; Ebersberger, I.; Wang, L.; Muench, C.; Stolz, A.; Brandes, R. P.; Tse, W. K. F.; Eimer, S.; Stainier, D. Y. R.; Legewie, S.; Zarnack, K.; Mueller-McNicoll, M.; Dikic, I.: Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. SCIENCE 386 (6723), S. 768 - 776 (2024)

Liu, Z.; Lu, C.; Ma, L.; Li, C.; Luo, H.; Liu, Y.; Liu, X.; Li, H.; Cui, Y.; Zeng, J. et al.; Bottasso-Arias, N.; Sinner, D.; Li, L.; Wang, J.; Stainier, D. Y. R.; Yin, W.: The T-Type Calcium Channel CACNA1H is Required for Smooth Muscle Cytoskeletal Organization During Tracheal Tubulogenesis. ADVANCED SCIENCE (2024)

Goumenaki, P.; Guenther, S.; Kikhi, K.; Looso, M.; Marin-Juez, R.; Stainier, D. Y. R.: The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration. NATURE CARDIOVASCULAR RESEARCH 3 (9), S. 1158 - 1176 (2024)

Bornhorst, D.; Hejjaji, A. V.; Steuter, L.; Woodhead, N. M.; Maier, P.; Gentile, A.; Alhajkadour, A.; Larrain, O. S.; Weber, M.; Kikhi, K. et al.; Guenther, S.; Huisken, J.; Tamplin, O. J.; Stainier, D. Y. R.; Gunawan, F.: The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish. NATURE COMMUNICATIONS 15 (1), 7589 (2024)

Gentile, A.; Albu, P. M.; Xu, Y.; Mortazavi , N.; da Silva, A.; Stainier, D. Y. R.; Gunawan, F.: Mechanical forces remodel the cardiac extracellular matrix during zebrafish development. DEVELOPMENT 151 (13), dev202310 (2024)

Gauvrit, S.; Zhao, S.; Rothbauer, U.; Stainier, D. Y. R.: A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo. DEVELOPMENT 151 (11), dev202122 (2024)

Ribeiro da Silva, A.; Gunawan, F.; Boezio, G. L. M.; Faure , E.; Theron , A.; Avierinos , J.-F.; Lim, S.; Shivam, G. J.; Ramadass, R.; Guenther, S. et al.; Looso, M.; Zaffran, S.; Juan, T.; Stainier, D. Y. R.: egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis. SCIENCE ADVANCES 10 (20), eadl0633 (2024)

Cardeira-da-Silva, J.; Wang, Q.; Sagvekar, P.; Mintcheva, J.; Latting, S.; Guenther, S.; Ramadass, R.; Yekelchyk, M.; Preussner, J.; Looso, M. et al.; Junker, J. P.; Stainier, D. Y. R.: Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish. NATURE COMMUNICATIONS 15 (1), 3637 (2024)

Albu, M.; Affolter, E.; Gentile, A.; Xu, Y.; Kikhi, K.; Howard, S.; Kuenne, C.; Priya, R.; Gunawan, F.; Stainier, D. Y. R.: Distinct mechanisms regulate ventricular and atrial chamber wall formation. NATURE COMMUNICATIONS 15 (1), 8159 (2024)

Ruijmbeek, C. W. B.; Filomena, H.; Idrees, H.; Housley, M. P.; Pestel, J.; Keller, L.; Lai, J. K. H.; Linde, J.; Willemsen , R.; Piesker, J. et al.; Al-Hassnan, Z. N.; Almesned , A.; Dalinghaus , M.; van den Bersselaar, L. M.; van Slegtenhorst, M. A.; Tessadori, F.; Bakkers, J.; van Ham, T. J.; Stainier, D.; Verhagen , J. M. A.; Reischauer, S.: Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization. JCI INSIGHT 8 (17), e168247 (2023)

Welker, J. M.; Serobyan, V.; Esfahani , E. Z.; Stainier, D. Y. R.: Partial sequence identity in a 25-nucleotide long element is sufficient for transcriptional adaptation in the Caenorhabditis elegans act-5/act-3 model. PLOS GENETICS 19 (6), e1010806 (2023)

Boezio, G. L. M.; Zhao, S.; Gollin, J.; Priya, R.; Mansingh, S.; Guenther, S.; Fukuda, N.; Gunawan, F.; Stainier, D. Y. R.: The developing epicardium regulates cardiac chamber morphogenesis by promoting cardiomyocyte growth. DISEASE MODELS & MECHANISMS 16 (5), dmm049571 (2023)

Hussmann, M.; Schulte, D.; Weischer, S.; Carlantoni, C.; Nakajima, H.; Mochizuki, N.; Stainier, D. Y. R.; Zobel, T.; Koch, M.; Schulte-Merker, S. et al.; Bautch, V. L.: Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner. ELIFE 12, e82969 (2023)