Publications of Xiang Zheng

Zheng, X.; Sarode, P.; Weigert , A.; Turkowski, K.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Winter , H.; Stenzinger, A.; Reu, S. et al.; Grimminger, F.; Stiewe, T.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. CANCER RESEARCH 83 (14), pp. 2345 - 2357 (2023)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Zheng, X.; Mansouri, S.; Krager, A.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Wheelock, C. E.; Savai, R.: Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment. EUROPEAN RESPIRATORY REVIEW 29 (157), 200134 (2020)

Salazar, Y.; Zheng, X.; Brunn, D.; Raifer, H.; Picard, F.; Zhang, Y.; Winter, H.; Guenther, S.; Weigert, A.; Weigmann, B. et al.; Dumoutier, L.; Renauld, J.-C.; Waisman, A.; Schmall, A.; Tufman, A.; Fink, L.; Bruene, B.; Bopp, T.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Huber, M.; Savai, R.: Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer. JOURNAL OF CLINICAL INVESTIGATION 130 (7), pp. 3560 - 3575 (2020)

Sarode, P.; Zheng, X.; Giotopoulou, G. A.; Weigert, A.; Kuenne, C.; Guenther, S.; Friedrich, A.; Gattenloehner, S.; Stiewe, T.; Bruene, B. et al.; Grimminger, F.; Stathopoulos, G. T.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Reprogramming of tumor-associated macrophages by targeting beta-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer. SCIENCE ADVANCES 6 (23), eaaz6105 (2020)

Zheng, X.; Weigert, A.; Reu, S.; Guenther, S.; Mansouri, S.; Bassaly, B.; Gattenlohner, S.; Grimminger, F.; Pullamsetti, S. S.; Seeger, W. et al.; Winter, H.; Savai, R.: Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small Cell Lung Carcinoma. CANCER RESEARCH 80 (20), pp. 4414 - 4425 (2020)

Solimani, F.; Pollmann, R.; Schmidt, T.; Schmidt, A.; Zheng, X.; Savai, R.; Muehlenbein, S.; Pickert, J.; Eubel, V.; Moebs, C. et al.; Eming, R.; Hertl, M.: Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus. FRONTIERS IN IMMUNOLOGY 10, 1808 (2019)

Sarode, P.; Zheng, X.; Weigert, A.; Tretyn, A.; Guenther, S.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Savai, R.: Reprogramming of Tumor Associated Macrophages by Modulating Wnt beta-Catenin Signalling in Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)

Savai, R.; Asafova, A.; Zheng, X.; Schmall, A.; Weigert, A.; Pullamsetti, S. S.; Seeger, W.: Circulating Fibrocytes Depletion Results In Reduced Lung Tumor Growth And Metastasis By Modulating Macrophage Phenotype, Angiogenesis And Endothelin System. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 195 (2017)

Zheng, X.; Sarode, P.; Weigert, A.; Guenther, S.; Chelladurai, P.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Re-Education Of Tumor-Associated Macrophages By Modulating Histone Deacetylases In Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 195 (2017)

Zheng, X.; Turkowski, K.; Mora, J.; Brne, B.; Seeger, W.; Weigert, A.; Savai, R.: Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy. ONCOTARGET 8 (29), pp. 48436 - 48452 (2017)