Publications of Johannes Graumann

Maroli, G.; Scha, A.; Guenther, S.; -Gonzalez, C. G.; Rupp, S.; Schlierbach, H.; Chen, Y.; Graumann, J.; Wietelmann, A.; Kim, J. et al.; Braun, T.: Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 193, pp. 53 - 66 (2024)

Brichkina, A.; Ems, M.; Suezov, R.; Singh, R.; Lutz, V.; Picard, F. S. R.; Nist, A.; Stiewe, T.; Graumann, J.; Daude, M. et al.; Diederich, W. E.; Finkernagel, F.; Chung, H.-R.; Bartsch, D. K.; Roth, K.; Keber, C.; Denkert, C.; Huber, M.; Gress, T. M.; Lauth, M.: DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer. GUT (2024)

Neuhaus, F.; Lieber, S.; Shinkevich, V.; Steitz, A. M.; Raifer, H.; Roth, K.; Finkernagel, F.; Worzfeld, T.; Burchert, A.; Keber, C. et al.; Nist, A.; Stiewe, T.; Reinartz, S.; Beutgen, V. M.; Graumann, J.; Pauck, K.; Garn, H.; Gaida, M.; Mueller, R.; Huber, M.: Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells. CLINICAL AND TRANSLATIONAL MEDICINE 14 (4), e1604 (2024)

Voelkel, S.; Tarawneh, T. S.; Sacher, L.; Bhagwat, A. M.; Karim, I.; Mack, H. I. D.; Wiesmann, T.; Beutel, B.; Hoyer, J.; Keller, C. et al.; Renz, H.; Burchert, A.; Neubauer, A.; Graumann, J.; Skevaki, C.; Mack, E. K. M.: Serum proteomics hint at an early T-cell response and modulation of SARS-CoV-2-related pathogenic pathways in COVID-19-ARDS treated with Ruxolitinib. FRONTIERS IN MEDICINE 10, 1176427 (2023)

Li, R.; Shao, J.; Jin, Y. J.; Haruya, K.; Ong, Y. T.; Troidl, K.; Quan, Q.; Wang, L.; Bonnavion, R.; Wietelmann, A. et al.; Helmbacher , F.; Potente, M.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2. NATURE COMMUNICATIONS 14 (1), 1980 (2023)

Ojasalu, K.; Lieber, S.; Sokol, A.; Nist, A.; Stiewe, T.; Bullwinkel, I.; Finkernagel, F.; Reinartz, S.; Mueller-Bruesselbach, S.; Grosse, R. et al.; Graumann, J.; Mueller, R.: The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis. THERANOSTICS 13 (6), pp. 1921 - 1948 (2023)

Sivakumar, S.; Lieber, S.; Librizzi, D.; Keber, C.; Sommerfeld, L.; Finkernagel, F.; Roth, K.; Reinartz, S.; Bartsch, J. W.; Graumann, J. et al.; Mueller-Bruesselbach, S.; Mueller, R.: Basal cell adhesion molecule promotes metastasis-associated processes in ovarian cancer. CLINICAL AND TRANSLATIONAL MEDICINE 13 (1), e1176 (2023)

Garcia-Gonzalez, C.; Dieterich, C.; Maroli, G.; Wiesnet, M.; Wietelmann, A.; Li, X.; Yuan, X.; Graumann, J.; Stellos, K.; Kubin, T. et al.; Schneider, A.; Braun, T.: ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. CIRCULATION RESEARCH 131 (7), pp. 580 - 597 (2022)

Woods, M. L.; Weiss, A.; Sokol, A. M.; Graumann, J.; Boettger, T.; Richter, A. M.; Schermuly, R. T.; Dammann, R. H.: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. CANCER GENE THERAPY (2022)

Hammoud, M. K.; Dietze, R.; Pesek, J.; Finkernagel, F.; Unger, A.; Bieringer, T.; Nist, A.; Stiewe, T.; Bhagwat, A. M.; Nockher, W. A. et al.; Reinartz, S.; Muller-Brusselbach, S.; Graumann, J.; Mueller, R.: Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures. MOLECULAR ONCOLOGY (2022)

Kudryashova V, T.; Dabral, S.; Nayakanti, S.; Ray, A.; Goncharov, D. A.; Avolio, T.; Shen, Y.; Rode, A.; Pena, A.; Jiang, L. et al.; Lin, D.; Baust, J.; Bachman, T. N.; Graumann, J.; Ruppert, C.; Guenther, A.; Schmoranzer, M.; Grobs, Y.; Lemay, S. E.; Tremblay, E.; Breuils-Bonnet, S.; Boucherat, O.; Mora, A. L.; DeLisser, H.; Zhao, J.; Zhao, Y.; Bonnet, S.; Seeger, W.; Pullamsetti, S. S.; Goncharova, E. A.: Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. CIRCULATION RESEARCH 130 (5), pp. 760 - 778 (2022)

Gadd, D. A.; Hillary, R. F.; McCartney, D. L.; Zaghlool, S. B.; Stevenson, A. J.; Cheng, Y.; Fawns-Ritchie, C.; Nangle, C.; Campbell, A.; Flaig, R. et al.; Harris, S. E.; Walker, R. M.; Shi, L.; Tucker-Drob, E. M.; Gieger, C.; Peters, A.; Waldenberger, M.; Graumann, J.; McRae, A. F.; Deary, I. J.; Porteous, D. J.; Hayward, C.; Visscher, P. M.; Cox, S. R.; Evans, K. L.; McIntosh, A. M.; Suhre, K.; Marioni, R. E.: Epigenetic scores for the circulating proteome as tools for disease prediction. ELIFE 11, e71802 (2022)

Sarvari, P.; Rasouli, S. J.; Allanki, S.; Stone, O. A.; Sokol, A. M.; Graumann, J.; Stainier, D. Y. R.: The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish. DEVELOPMENTAL BIOLOGY 480, pp. 1 - 12 (2021)

Sommerfeld, L.; Finkernagel, F.; Jansen, J. M.; Wagner, U.; Nist, A.; Stiewe, T.; Mueller-Bruesselbach, S.; Sokol, A. M.; Graumann, J.; Reinartz, S. et al.; Mueller, R.: The multicellular signalling network of ovarian cancer metastases. CLINICAL AND TRANSLATIONAL MEDICINE 11 (11), e633 (2021)

Jin, Y.-J.; Chennupati, R.; Li, R.; Liang, G.; Wang, S.; Iring, A.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION 131 (21), e145734 (2021)

Matias-Garcia, P. R.; Wilson, R.; Guo, Q.; Zaghlool, S. B.; Eales, J. M.; Xu, X.; Charchar, F. J.; Dormer, J.; Maalmi, H.; Schlosser, P. et al.; Elhadad, M. A.; Nano, J.; Sharma, S.; Peters, A.; Fornoni, A.; Mook-Kanamori, D. O.; Winkelmann, J.; Danesh, J.; Di Angelantonio, E.; Ouwehand, W. H.; Watkins, N. A.; Roberts, D. J.; Petrera, A.; Graumann, J.; Koenig, W.; Hveem, K.; Jonasson, C.; Koettgen, A.; Butterworth, A.; Prunotto, M.; Hauck, S.; Herder, C.; Suhre, K.; Gieger, C.; Tomaszewski, M.; Teumer, A.; Waldenberger, M.: Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 32 (7), pp. 1747 - 1763 (2021)

Tan, D. S.; Chen, Y.; Gao, Y.; Bednarz, A.; Wei, Y.; Malik, V.; Ho, D. H.-H.; Weng, M.; Ho, S. Y.; Srivastava, Y. et al.; Velychko, S.; Yang, X.; Fan, L.; Kim, J.; Graumann, J.; Stormo, G. D.; Braun, T.; Yan, J.; Schoeler, H. R.; Jauch, R.: Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering. MOLECULAR BIOLOGY AND EVOLUTION 38 (7), pp. 2854 - 2868 (2021)

Elhadad, M. A.; Wilson, R.; Zaghlool, S. B.; Huth, C.; Gieger, C.; Grallert, H.; Graumann, J.; Rathmann, W.; Koenig, W.; Sinner, M. F. et al.; Hveem, K.; Suhre, K.; Thorand, B.; Jonasson, C.; Waldenberger, M.; Peters, A.: Metabolic syndrome and the plasma proteome: from association to causation. CARDIOVASCULAR DIABETOLOGY 20 (1), 111 (2021)

Majeed, Y.; Halabi, N.; Madani, A. Y.; Engelke, R.; Bhagwat, A. M.; Abdesselem, H.; Agha V, M.; Vakayil, M.; Courjaret, R.; Goswami, N. et al.; Ben Hamidane, H.; Elrayess, M. A.; Rafii, A.; Graumann, J.; Schmidt, F.; Mazloum, N. A.: SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways. SCIENTIFIC REPORTS 11 (1), 8177 (2021)

Zaghlool, S. B.; Sharma, S.; Molnar, M.; Matias-Garcia, P. R.; Elhadad, M. A.; Waldenberger, M.; Peters, A.; Rathmann, W.; Graumann, J.; Gieger, C. et al.; Grallert, H.; Suhre, K.: Revealing the role of the human blood plasma proteome in obesity using genetic drivers. NATURE COMMUNICATIONS 12 (1), 1279 (2021)