Publications of Stefan Offermanns

Wedel, S.; Hahnefeld, L.; Alnouri, M. W.; Offermanns, S.; Hausch, F.; Geisslinger, G.; Sisignano, M.: The FKBP51 Inhibitor SAFit2 Restores the Pain-Relieving C16 Dihydroceramide after Nerve Injury. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (22), 14274 (2022)

Gogiraju, R.; Gachkar, S.; Velmeden, D.; Bochenek, M. L.; Zifkos, K.; Hubert, A.; Muenzel, T.; Offermanns, S.; Schaefer, K.: Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. THROMBOSIS AND HAEMOSTASIS 122 (10), pp. 1814 - 1826 (2022)

Wang, S.; Wang, B.; Shi, Y.; Moeller, T.; Stegmeyer I, R.; Strilic, B.; Li, T.; Yuan, Z.; Wang, C.; Wettschureck, N. et al.; Vestweber, D.; Offermanns, S.: Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. BLOOD 140 (3), pp. 171 - 183 (2022)

Xu, R.; Hoess, C.; Swiercz, J. M.; Brandt, D. T.; Lutz, V.; Petersen, N.; Li, R.; Zhao, D.; Oleksy, A.; Creigh-Pulatmen, T. et al.; Trokter, M.; Fedorova, M.; Atzberger, A.; Strandby, R. B.; Olsen, A. A.; Achiam, M. P.; Matthews, D.; Huber, M.; Groene, H.-J.; Offermanns, S.; Worzfeld, T.: A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers. SCIENCE TRANSLATIONAL MEDICINE 14 (654), eabf1922 (2022)

Gupta, R.; Wang, M.; Ma, Y.; Offermanns, S.; Whim, M. D.: The beta-Hydroxybutyrate-GPR109A Receptor Regulates Fasting-induced Plasticity in the Mouse Adrenal Medulla. ENDOCRINOLOGY 163 (7), bqac077 (2022)

Liang, G.; Wang, S.; Shao, J.; Jin, Y.-J.; Xu, L.; Yan, Y.; Guenther, S.; Wang, L.; Offermanns, S.: Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. CIRCULATION RESEARCH 130 (11), pp. 1647 - 1659 (2022)

Keshavarz, M.; Tabrizi, S. F.; Ruppert, A.-L.; Pfeil, U.; Schreiber, Y.; Klein, J.; Brandenburger, I.; Lochnit, G.; Bhushan, S.; Perniss, A. et al.; Deckmann, K.; Hartmann, P.; Meiners, M.; Mermer, P.; Rafiq, A.; Winterberg, S.; Papadakis, T.; Thomas, D.; Angioni, C.; Oberwinkler, J.; Chubanov, V.; Gudermann, T.; Gaertner, U.; Offermanns, S.; Schuetz, B.; Kummer, W.: Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. SCIENCE IMMUNOLOGY 7 (69), eabf6734 (2022)

Briquet, M.; Rocher, A.-B.; Alessandri, M.; Rosenberg, N.; Abrantes, H. d. C.; Wellbourne-Wood, J.; Schmuziger, C.; Ginet, V.; Puyal, J.; Pralong, E. et al.; Daniel, R. T.; Offermanns, S.; Chatton, J.-Y.: Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 0271678X221080324 (2022)

Schebb, N. H.; Kuehn, H.; Kahnt, A. S.; Rund, K. M.; O'Donnell, V. B.; Flamand, N.; Peters-Golden, M.; Jakobsson, P.-J.; Weylandt, K. H.; Rohwer, N. et al.; Murphy, R. C.; Geisslinger, G.; FitzGerald, G. A.; Hanson, J.; Dahlgren, C.; Alnouri, M. W.; Offermanns, S.; Steinhilber, D.: Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? FRONTIERS IN PHARMACOLOGY 13, 838782 (2022)

Stamatiades, G. A.; Toufaily, C.; Kim, H. K.; Zhou, X.; Thompson, I. R.; Carroll, R. S.; Chen, M.; Weinstein, L. S.; Offermanns, S.; Boehm, U. et al.; Bernard, D. J.; Kaiser, U. B.: Deletion of G alpha(q/11) or G alpha(s) Proteins in Gonadotropes Differentially Affects Gonadotropin Production and Secretion in Mice. ENDOCRINOLOGY 163 (2), bqab247 (2022)

Borsodi, K.; Balla, H.; Molnar, P. J.; Lenart, A.; Kenessey, I.; Horvath, A.; Keszthelyi, A.; Romics, M.; Majoros, A.; Nyirady, P. et al.; Offermanns, S.; Benyo, Z.: Signaling Pathways Mediating Bradykinin-Induced Contraction in Murine and Human Detrusor Muscle. FRONTIERS IN MEDICINE 8, 745638 (2022)

Wang, S.; Wang, B.; Shi, Y.; Moller, T.; Stegmeyer, R. I.; Strilic, B.; Li, T.; Yuan, Z.; Wang, C.; Wettschureck, N. et al.; Vestweber, D.; Offermanns, S.: Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. Blood (2022)

Gurusamy, M.; Tischner, D.; Shao, J.; Klatt, S.; Zukunft, S.; Bonnavion, R.; Guenther, S.; Siebenbrodt, K.; Kestner, R.-I.; Kuhlmann, T. et al.; Fleming, I.; Offermanns, S.; Wettschureck, N.: G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS 12 (1), 6798 (2021)

Ishihama, S.; Yoshida, S.; Yoshida, T.; Mori, Y.; Ouchi, N.; Eguchi, S.; Sakaguchi, T.; Tsuda, T.; Kato, K.; Shimizu, Y. et al.; Ohashi, K.; Okumura, T.; Bando, Y. K.; Yagyu, H.; Wettschureck, N.; Kubota, N.; Offermanns, S.; Kadowaki, T.; Murohara, T.; Takefuji, M.: LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia. FASEB JOURNAL 35 (12), e22048 (2021)

Jin, Y.-J.; Chennupati, R.; Li, R.; Liang, G.; Wang, S.; Iring, A.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION 131 (21), e145734 (2021)

Alexander, S. P. H.; Christopoulos, A.; Davenport, A. P.; Kelly, E.; Mathie, A.; Peters, J. A.; Veale, E. L.; Armstrong, J. F.; Faccenda, E.; Harding, S. D. et al.; Pawson, A. J.; Southan, C.; Davies, J. A.; Abbracchio, M. P.; Alexander, W.; Al-hosaini, K.; Baeck, M.; Barnes, N. M.; Bathgate, R.; Beaulieu, J.-M.; Bernstein, K. E.; Bettler, B.; Birdsall, N. J. M.; Blaho, V.; Boulay, F.; Bousquet, C.; Braeuner-Osborne, H.; Burnstock, G.; Calo, G.; Castano, J. P.; Catt, K.; Ceruti, S.; Chazot, P.; Chiang, N.; Chini, B.; Chun, J.; Cianciulli, A.; Civelli, O.; Clapp, L. H.; Couture, R.; Csaba, Z.; Dahlgren, C.; Dent, G.; Singh, K. D.; Douglas, S. D.; Dournaud, P.; Eguchi, S.; Escher, E.; Filardo, E. J.; Fong, T.; Fumagalli, M.; Gainetdinov, R. R.; de Gasparo, M.; Gerard, C.; Gershengorn, M.; Gobeil, F.; Goodfriend, T. L.; Goudet, C.; Gregory, K. J.; Gundlach, A. L.; Hamann, J.; Hanson, J.; Hauger, R. L.; Hay, D. L.; Heinemann, A.; Hollenberg, M. D.; Holliday, N. D.; Horiuchi, M.; Hoyer, D.; Hunyady, L.; Husain, A.; IJzerman, A. P.; Inagami, T.; Jacobson, K. A.; Jensen, R. T.; Jockers, R.; Jonnalagadda, D.; Karnik, S.; Kaupmann, K.; Kemp, J.; Kennedy, C.; Kihara, Y.; Kitazawa, T.; Kozielewicz, P.; Kreienkamp, H.-J.; Kukkonen, J. P.; Langenhan, T.; Leach, K.; Lecca, D.; Lee, J. D.; Leeman, S. E.; Leprince, J.; Li, X. X.; Williams, T. L.; Lolait, S. J.; Lupp, A.; Macrae, R.; Maguire, J.; Mazella, J.; McArdle, C. A.; Melmed, S.; Michel, M. C.; Miller, L. J.; Mitolo, V.; Mouillac, B.; Mueller, C. E.; Murphy, P.; Nahon, J.-L.; Ngo, T.; Norel, X.; Nyimanu, D.; Ocarroll, A.-M.; Offermanns, S.; Panaro, M. A.; Parmentier, M.; Pertwee, R. G.; Pin, J.-P.; Prossnitz, E. R.; Quinn, M.; Ramachandran, R.; Ray, M.; Reinscheid, R. K.; Rondard, P.; Rovati, G. E.; Ruzza, C.; Sanger, G. J.; Schoeneberg, T.; Schulte, G.; Schulz, S.; Segaloff, D. L.; Serhan, C. N.; Stoddart, L. A.; Sugimoto, Y.; Summers, R.; Tan, V. P.; Thal, D.; Thomas, W. (.; Timmermans, P. M. W. M.; Tirupula, K.; Tulipano, G.; Unal, H.; Unger, T.; Valant, C.; Vanderheyden, P.; Vaudry, D.; Vaudry, H.; Vilardaga, J.-P.; Walker, C. S.; Wang, J. M.; Ward, D. T.; Wester, H.-J.; Willars, G. B.; Woodruff, T. M.; Yao, C.; Ye, R. D.: THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. BRITISH JOURNAL OF PHARMACOLOGY 178 (Supplement 1), pp. S27 - S156 (2021)

Berillo, O.; Coelho, S. C.; Mahjoub, N.; Offermanns, S.; Paradis, P.; Schiffrin, E. L.: Aldosterone contributes to hypertension in malemice inducibly overexpressing human endothelin-1 in endothelium. JOURNAL OF HYPERTENSION 39 (9), pp. 1908 - 1917 (2021)

Grunddal, K. V.; Tonack, S.; Egerod, K. L.; Thompson, J. J.; Petersen, N.; Engelstoft, M. S.; Vagne, C.; Keinse, C.; Gradwohl, G.; Offermanns, S. et al.; Schwartz, T. W.: Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells. MOLECULAR METABOLISM 51, 101231 (2021)

Le Mercier, A.; Bonnavion, R.; Yu, W.; Alnouri, M. W.; Ramas, S.; Zhang, Y.; Jaeger, Y.; Roquid, K. A.; Jeong, H.-W.; Sivaraj, K. K. et al.; Cho, H.; Chen, X.; Strilic, B.; Sijmonsma, T.; Adams, R.; Schroeder, T.; Rieger, M. A.; Offemanns, S.: GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118 (17), e2021596118 (2021)

Molnar, P. J.; Der, B.; Borsodi, K.; Balla, H.; Borbas, Z.; Molnar, K.; Ruisanchez, E.; Kenessey, I.; Horvath, A.; Keszthelyi, A. et al.; Majoros, A.; Nyirady, P.; Offermanns, S.; Benyo, Z.: Isoprostanes evoke contraction of the murine and human detrusor muscle via activation of the thromboxane prostanoid TP receptor and Rho kinase. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 320 (4), pp. F537 - F547 (2021)