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Magnetresonanztomographie

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Group Leader:

Dr. Astrid Wietelmann

 

Group Member:

Ursula Hofmann (technical assistant)

Overview:

MRI (Magnetic Resonance Imaging) is a method suitable for studying in vivo and noninvasively inner organs and tissues using magnetic fields and radiofrequency pulses. In contrast to such devices as CT (Computed Tomography) it does not utilize ionizing radiation. MRI is a versatile technique with a variety of new applications in biomedicine. Not only MR allows visualization of structure of plants, animals, and humans and their organs, but also provides dynamic information about function and metabolism down to molecular level. Most of the MR imaging occurring in biological research is centered on a signal from hydrogen (1H) because of its proportionally large natural abundance in biological systems as well as the associated large magnetic moment. Other nuclei used in magnetic resonance imaging and spectroscopy are e.g. 13C or 31P.

Facilites and Equipment:

The group is equipped with a horizontal 7.05 T Bruker PharmaScan, operating at 300,51 MHz for 1H which we use to investigate organs (heart, vessels, brain, etc.) and extremities of small animals like mice, rats and newts. The nominal bore size of the magnet is 16 cm, with inserted gradient system (300mT/m) and rf (radio frequency, RF) coils the maximal useable bore size amounts in the moment to 6 cm. The system electronics are of type Bruker Avance III, controlled by a Linux PC with Paravision 5.1 for imaging and TopSpin 2.0 for high resolution spectroscopy.

 

For our in vivo measurements resonators with an inner diameter of 1.3, 2.5, 3.5, and 6.0 are available; partially our resonators are designed and constructed at our institute.

Contact:

Magnetic Resonance Imaging

Dr. Astrid Wietelmann

Max Planck Institute for Heart and Lung Research

Ludwigstrasse 43

D-61231 Bad Nauheim

Tel.: +49 (0)6032 705-1703 or -1720

© 2017 Max-Planck-Institut für Herz- und Lungenforschung, Bad Nauheim